Once you get sick on the show, there is an array of diagnosis while we wait for newer symptoms (that personally look impossible).. We know it's never Lupus. And eventually it comes down to something really weird.
It took me a while to even try on "House".... Similar to Doctor Who.. I'm an 'old' fan.
I remember "Fry and Laurie"... I adore the film "Peter's Friends"
And first and foremost...
This... This is the way I remember Hugh Laurie:
#2 is just beautiful for timing: